GeniLuc

We propose the genomic analysis of 200 lung tumours resected from patients with a high a priori likelihood of genetic susceptibility based on age of onset or family history. Complementary germ-line studies in these patients with this rare phenotype are ongoing. A novel combined analysis of somatic and germ-line genomic data will be used to evaluate the consequence of germ-line variation on the tumour’s characteristics and assist identification of novel susceptibility alleles for lung cancer.

Publications :

• N. Alcala et al. Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids. Nature Communications 2019, vol. 10, issue 1