NF-Y controls transcription

The ATGC platform has published a comprehensive genomic study in mouse embryonic stem cells , that describes NF-Y’s mechanistic critical role at promoters to direct the transcription machinery to the correct transcription start site while occluding alternative sites of sub-optimal transcription initiation.

Nat Commun. 2019 Jul 11;10(1):3072. doi : 10.1038/s41467-019-10905-7.