Sélection 2021

Tracy Rabilloud et al.
Single-cell profiling identifies pre-existing CD19-negative subclones in a B-ALL patient with CD19-negative relapse after CAR-T therapy
Nature Communications 2021, vol. 12, issue 1
doi: 10.1038/s41467-021-21168-6

Paul Gueguen et al.
Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in lung cancer
Science Immunology 2021, vol. 6, issue 55
doi: 10.1126/sciimmunol.abd5778

Aurélie Allais-Bonnet et al.
Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae
Molecular Biology and Evolution 2021
doi: 10.1093/molbev/msab021

Paul Jay et al.
Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms
Nature Genetics 2021, vol. 53, issue 3
doi: 10.1038/s41588-020-00771-1

Fabienne Bejjani et al.
Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers
Nucleic Acids Research 2021, vol. 49, issue 5
doi: 10.1093/nar/gkab053

François Rousset et al.
The impact of genetic diversity on gene essentiality within the Escherichia coli species
Nature Microbiology 2021, vol. 6, issue 3
doi: 10.1038/s41564-020-00839-y

Charlotte Pandiani et al.
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease
Cell Death & Differentiation 2021
doi: 10.1038/s41418-020-00730-7

Tomasz Chelmicki et al.
m6A RNA methylation regulates the fate of endogenous retroviruses
Nature 2021, vol. 591, issue 7849
doi: 10.1038/s41586-020-03135-1

Rafael Alcalá-Vida et al.
Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice
Nature Communications 2021, vol. 12, issue 1
doi: 10.1038/s41467-020-20605-2

Antoine Bernard et al.
The Tumor Microenvironment Impairs Th1 IFNγ Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA
Cancer Immunology Research 2021, vol. 9, issue 3
doi: 10.1158/2326-6066.cir-19-0679